Errors discovered

Accounting for data errors discovered from an audit in multiple linear regression.

A data coordinating team performed onsite audits and discovered discrepancies between the data sent to the coordinating center and that recorded at sites. We present statistical methods for incorporating audit results into analyses. This can be thought of as a measurement error problem, where the distribution of errors is a mixture with a point mass at 0. If the error rate is nonzero, then even...

Incidentally Discovered Hepatic Lesions

Historically, unsuspected incidental solid tumors of the liver were encountered only at the time of laparotomy when biopsy and definitive histologic diagnosis were obtainable. However, as cross-sectional imaging studies have become widely available and increasingly applied, the identification of unsuspected liver lesions has become common, and the appropriate means to address these lesions is a...

Who discovered messenger RNA?

The announcement of the discovery of messenger RNA (mRNA) and the cracking of the genetic code took place within weeks of each other in a climax of scientific excitement during the summer of 1961. Although mRNA is of decisive importance to our understanding of gene function, no Nobel Prize was awarded for its discovery. The large number of people involved, the complex nature of the results, and...

Spontaneous Vortex Phase Discovered?

where $ B ­ = 3 $ A, $ M is magnetization and c is the superconducting order parameter. It was shown that a stable spiral phase, where superconductivity coexists with spiraling magnetization, or a spontaneous vortex phase, where magnetization is more or less uniform in the system but vortices are generated without an external magnetic field, may occur. Subsequently, the spiral phase was discove...

Who Discovered Hemophilia?